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R K Berge Selected Research

1-(carboxymethylthio)tetradecane

11/2009Dietary supplementation of tetradecylthioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed on high-fat diets.
11/2009Increased survival by feeding tetradecylthioacetic acid during a natural outbreak of heart and skeletal muscle inflammation in S0 Atlantic salmon, Salmo salar L.
4/2009Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation.
5/2003Immunomodulating effects of 3-thia fatty acids in activated peripheral blood mononuclear cells.
11/2002Antiproliferative effects of a non-beta-oxidizable fatty acid, tetradecylthioacetic acid, in native human acute myelogenous leukemia blast cultures.
11/2001Sustained retention of tetradecylthioacetic acid after local delivery reduces angioplasty-induced coronary stenosis in the minipig.
11/2001Tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways.
10/2001Tetradecylthioacetic acid reduces stenosis development after balloon angioplasty injury of rabbit iliac arteries.
3/2001Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status.
3/2001Optimization of methods and treatment conditions for studying effects of fatty acids on cell growth.

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R K Berge Research Topics

Disease

5Inflammation (Inflammations)
01/2019 - 05/2003
4Glioma (Gliomas)
01/2005 - 03/2001
4Necrosis
10/2004 - 03/2000
3Common Variable Immunodeficiency
01/2019 - 03/2000
3Insulin Resistance
01/2005 - 06/2000
2Atherosclerosis
10/2020 - 05/2003
2Dysbiosis
01/2019 - 11/2016
2Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
11/2016 - 11/2005
2Coronary Artery Disease (Coronary Atherosclerosis)
06/2015 - 08/2001
2Heart Failure
06/2015 - 09/2011
2Body Weight (Weight, Body)
11/2009 - 06/2000
2Iron Deficiencies
11/2005 - 05/2003
2Dyslipidemias (Dyslipidemia)
10/2003 - 06/2000
2Neoplasms (Cancer)
11/2001 - 03/2001
2Pathologic Constriction (Stenosis)
11/2001 - 10/2001
1Stable Angina
10/2020
1Coronary Disease (Coronary Heart Disease)
10/2020
1Myocardial Infarction
10/2020
1Liver Diseases (Liver Disease)
01/2019
1Weight Gain
06/2015
1Weight Loss (Weight Reduction)
06/2015
1Hyperphagia (Overeating)
06/2015
1Acute Necrotizing Pancreatitis
11/2009
1Type 2 Diabetes Mellitus (MODY)
04/2009
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2005
1Crohn Disease (Crohn's Disease)
05/2003
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
11/2002
1Coronary Stenosis (Coronary Artery Stenosis)
11/2001
1Unstable Angina
02/2001
1Acute Coronary Syndrome
02/2001
1HIV Infections (HIV Infection)
10/2000
1Hyperinsulinism (Hyperinsulinemia)
06/2000

Drug/Important Bio-Agent (IBA)

101-(carboxymethylthio)tetradecaneIBA
11/2009 - 03/2001
8Fatty Acids (Saturated Fatty Acids)IBA
09/2011 - 03/2001
4AntioxidantsIBA
05/2003 - 10/2000
3CholesterolIBA
06/2015 - 10/2004
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2001 - 03/2000
2trimethyloxamine (trimethylamine N-oxide)IBA
10/2020 - 06/2015
2Carnitine (L-Carnitine)FDA LinkGeneric
10/2020 - 06/2015
2LipopolysaccharidesIBA
01/2019 - 11/2016
2Immunoglobulins (Immunoglobulin)IBA
11/2016 - 03/2000
2Antipsychotic Agents (Antipsychotics)IBA
06/2015 - 01/2005
2PPAR alphaIBA
04/2009 - 06/2000
2Glucose (Dextrose)FDA LinkGeneric
04/2009 - 10/2003
2LipidsIBA
01/2005 - 10/2003
2Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
10/2003 - 08/2001
2Interleukin-10 (Interleukin 10)IBA
05/2003 - 03/2000
2Glutathione (Reduced Glutathione)IBA
11/2001 - 10/2000
2ThymidineIBA
03/2001 - 03/2001
2NeopterinIBA
10/2000 - 03/2000
1Riboflavin (Vitamin B2)FDA LinkGeneric
10/2020
1trimethyllysineIBA
10/2020
1Rifaximin (L 105)FDA Link
01/2019
1Anti-Bacterial Agents (Antibiotics)IBA
01/2019
1Immunoglobulin M (IgM)IBA
11/2016
1Biomarkers (Surrogate Marker)IBA
11/2016
116S Ribosomal RNAIBA
11/2016
1Immunoglobulin A (IgA)IBA
11/2016
1Olanzapine (Zyprexa)FDA Link
06/2015
1Phosphatidylcholines (Phosphatidylcholine)IBA
06/2015
1AcidsIBA
09/2011
111-octadecenoic acid (vaccenic acid)IBA
09/2011
1Brain Natriuretic Peptide (Natrecor)FDA Link
09/2011
1C-Reactive ProteinIBA
09/2011
1lardIBA
11/2009
1Pharmaceutical PreparationsIBA
04/2009
1ferrous sulfateFDA Link
11/2005
1teferrolIBA
11/2005
1Clozapine (Clozaril)FDA LinkGeneric
01/2005
1Haloperidol (Haldol)FDA LinkGeneric
01/2005
1Fatty Acid Synthases (Fatty Acid Synthase)IBA
01/2005
1Stearoyl-CoA DesaturaseIBA
01/2005
1Messenger RNA (mRNA)IBA
10/2003
1LeptinIBA
10/2003
1Insulin (Novolin)FDA Link
10/2003
1CytokinesIBA
05/2003
1ferrous fumarate (fumar)FDA LinkGeneric
05/2003
1IronIBA
05/2003
1Reactive Oxygen Species (Oxygen Radicals)IBA
05/2003
1Phenobarbital (Luminal)FDA Link
11/2001
1LigandsIBA
11/2001
1Cytochromes c (Cytochrome c)IBA
11/2001
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
11/2001
1PPAR deltaIBA
11/2001
1PPAR gammaIBA
11/2001
1SulfurIBA
11/2001
1alpha-TocopherolFDA Link
03/2001
1Palmitic Acid (Hexadecanoic Acid)IBA
03/2001
1S-ethyl glutathioneIBA
02/2001
1ChemokinesIBA
02/2001
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
02/2001
1RNA (Ribonucleic Acid)IBA
10/2000
1Ascorbic Acid (Vitamin C)FDA LinkGeneric
10/2000
1Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
10/2000
1Acetylcysteine (Siran)FDA LinkGeneric
10/2000
1Sulfhydryl Compounds (Thiols)IBA
10/2000
1ThiazolidinedionesIBA
06/2000
1ciprofibrateIBA
06/2000

Therapy/Procedure

1Therapeutics
11/2001
1Aftercare (After-Treatment)
03/2001